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Can gamers beat the protein chemistry challenge?

Imagine employing a legion of computer gaming fanatics to channel their obsession into finding solutions to some of the thorniest problems in protein chemistry. That's what University of Washington Read more...

Vaccine a success for human-to-human H5N1 case

A case of human-to-human transmission of bird flu has been confirmed in China, but authorities say it is another instance where the spread of the disease has been limited to a close blood relative. Read more...
Tags: vaccine   pandemic   outbreak   Avian flu   Sinovac  

Has the Gates Foundation created a malaria 'cartel'?

The Bill & Melinda Gates Foundation has come under a rare attack for its contributions to research efforts targeted at malaria. The world's top malaria scientists are "locked up in a Read more...

Research group mapping 1,000 genomes

An international research consortium is launching the 1,000 Genomes Project, mapping the genomes of a thousand different people in an effort to shine a bright research light on the influence of Read more...

New vaccine may stop, slow Alzheimer's

Scientists at Oklahoma Medical Research Foundation are reporting success in advancing an experimental, preclinical vaccine that can prevent or slow Alzheimer's. The researchers, led by Dr. Jordan Read more...
Tags: proteins   vaccine   plaque   preclinical  

Biosecurity expert points to threat of smallpox attack

Ian Ramshaw, the director of the National Centre for Biosecurity at the Australian National University, used a meeting held on the 30th anniversary of the eradication of smallpox to raise warnings Read more...
Tags: vaccine  

Pathway discovered to influence fat accumulation

In a remarkable breakthrough for weight research, scientists have reported the discovery of a neurochemical pathway that stimulates the accumulation of fat in animals laboring under chronically high stress and exposed to a diet of junk food. Inhibiting the pathway prevented weight gain in mice but selectively spurring the mechanism allowed for the strategic accumulation of weight--potentially opening a new pathway to mold larger breasts, firmer buttocks and younger faces.

Zofia …

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New drug controls body's signals for eating

A research team at Hebrew University on Jerusalem has developed a drug that mimics the activity of the hormone aMSH, which spurs the feeling of fullness. The hormone binds to a receptor in the brain that sends out the signal to the body that it is full. The researchers, led by a grad student, developed a synthetic peptide called BL-3020 that was able to enter the bloodstream, make its way to the receptor and emit the 'full' signal. Testing the therapy on mice over 24 hours, researchers …

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Gene deletion study defuses disease risk from fat

A new study in mice raises the possibility that humans may one day be able to eat any kind of fat they want without raising their risk of heart disease. The study involved deleting a gene in the mice that causes production of ACAT2, an enzyme that alters the molecular structure of cholesterol so that it can be transported to the body's cells.

"We deleted an enzyme in mice and they could eat any type of fat and not get heart disease," said Lawrence Rudel, Ph.D., a professor of …

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Drug switches on fat-burning gene in mice

Ronald M. Evans, an investigator at The Salk Institute in San Diego, has developed a drug that switches on the PPAR-d gene in mice, protecting them against weight gain from high-calorie and high-fat diets. The drug--which mimics fat--triggers their metabolisms and generates a physical response similar to exercising. After treatment, the mice had lower levels of fatty acids, triglyceride and sugar levels. These mice also exhibited much greater stamina, allowing them to exercise twice as …

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