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Diabetes breakthrough relies on single injection

A single injection of the hormone leptin proved sufficient to heal terminally ill mice sickened by type 1 diabetes. Leptin lowered blood glucose levels to a normal range and maintained that level for Read more...

Stem cell revolutionaries take on big challenges

OncoMed's Michael Clarke, George Q. Daly at the Harvard Stem Cell Institute, Sir Martin Evans from Cardiff University and Rene Hen from BrainCells/Columbia University are among 12 stem cell Read more...

Geron reports breakthrough in stem cell research

Geron stock got a big boost just days ago when researchers announced that they had coaxed embryonic stem cells into clusters that produced insulin in response to elevated levels of glucose. The work points to a potential cure for Type 1 diabetes, which had investors cheering up its stock by about 10 percent. Some analysts note that the company has been the subject of a considerable amount of press attention, which hasn't hurt its stock price.

"These studies show that the islet-like …

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ALSO NOTED: Researchers probe breast cancer therapies; Spleen cells used to reverse diabetes; Study probes proteins role in mem

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University of Edinburgh and the Riken Genomic Research Centre in Japan have begun a five-year project to probe why breast cancer therapies work in some patients and not in others. Their work could lead to way to more personalized therapies. Release

A study from the National Institutes of Health reaffirms the conclusion of earlier studies that adult …

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Team coaxes stem cells to produce insulin

Researchers at San Diego-based Novocell have been able to turn embryonic stem cells into pancreatic cells capable of producing insulin. Their work points the way to repairing the destruction of cells that create insulin, a condition that causes type 1 diabetes. Observers of the work say they were particularly struck by the efficiency of the conversion of embryonic stem cells into pancreatic cells. Novocell Chief Scientific Officer Emmanuel Baetge told The New York Times

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Transplants offer possible new cure for diabetes

Taking precursors of the pancreas of embryonic pigs and transplanting them into rats was an effective way to get them to start producing insulin without triggering a response from the immune system, according to researchers from Washington University School of Medicine in St. Louis. As a result, they were able to cure not only type 1 but type 2 diabetes in the animal models. Their work points to a possible therapy for type 2 diabetes that won't require powerful immune …

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Researchers unveil new insights into regulatory T cells

A research team at the Medical College of Georgia has determined that regulatory T cells learn to distinguish between normal body tissue and outside invaders early in life. If researchers can learn how to control T cell education in childhood, it could form the basis for preventing autoimmune diseases like type 1 diabetes or lupus. The team also concluded that regulatory T cells are produced in the thymus, a small organ located in the chest area. The regulatory T cells learn in the thymus …

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