Scripps Research Institute news from FierceBioResearcher

Australian scientists say that targeting angiotensin converting enzyme (ACE) can be an effective way to spur weight loss and prevent diabetes. And the research demonstrates that ACE-inhibitors could Read more...

Technology A team at the Institute for BioNanotechnology in Medicine at Northwestern University has created a "miniature laboratory" from one polymer and one small molecule in which human stem cells Read more...

A novel vaccine developed at The Scripps Research Institute at La Jolla may offer a new way to block infections without sparking bacterial resistance--a process that gradually dilutes the Read more...

More Research French researchers say they have successfully tested a new drug--IDC16--that interferes with a human splicing protein that plays a critical role in the development of AIDS. Read more...

The Max Planck Society is considering developing a 100,000-square foot research facility in Florida Atlantic University's Jupiter campus. The site is close to another research center in Palm Beach Read more...

A collaboration between the Scripps Research Institute and IBM to find new antidotes to flu before new mutations surface is making some initial progress. Dubbed Project Checkmate, scientists are Read more...

In a remarkable breakthrough for weight research, scientists have reported the discovery of a neurochemical pathway that stimulates the accumulation of fat in animals laboring under chronically high stress and exposed to a diet of junk food. Inhibiting the pathway prevented weight gain in mice but selectively spurring the mechanism allowed for the strategic accumulation of weight--potentially opening a new pathway to mold larger breasts, firmer buttocks and younger faces.

Zofia …

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A research team at Hebrew University on Jerusalem has developed a drug that mimics the activity of the hormone aMSH, which spurs the feeling of fullness. The hormone binds to a receptor in the brain that sends out the signal to the body that it is full. The researchers, led by a grad student, developed a synthetic peptide called BL-3020 that was able to enter the bloodstream, make its way to the receptor and emit the 'full' signal. Testing the therapy on mice over 24 hours, researchers …

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A new study in mice raises the possibility that humans may one day be able to eat any kind of fat they want without raising their risk of heart disease. The study involved deleting a gene in the mice that causes production of ACAT2, an enzyme that alters the molecular structure of cholesterol so that it can be transported to the body's cells.

"We deleted an enzyme in mice and they could eat any type of fat and not get heart disease," said Lawrence Rudel, Ph.D., a professor of …

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Ronald M. Evans, an investigator at The Salk Institute in San Diego, has developed a drug that switches on the PPAR-d gene in mice, protecting them against weight gain from high-calorie and high-fat diets. The drug--which mimics fat--triggers their metabolisms and generates a physical response similar to exercising. After treatment, the mice had lower levels of fatty acids, triglyceride and sugar levels. These mice also exhibited much greater stamina, allowing them to exercise twice as …

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