pyy news from FierceBioResearcher

A new imaging probe has highlighted how the human body's hunger pathways operate, illustrating how new therapies could be developed to tame obesity. Rachel Batterham and a team of researchers at Read more...

In a remarkable breakthrough for weight research, scientists have reported the discovery of a neurochemical pathway that stimulates the accumulation of fat in animals laboring under chronically high stress and exposed to a diet of junk food. Inhibiting the pathway prevented weight gain in mice but selectively spurring the mechanism allowed for the strategic accumulation of weight--potentially opening a new pathway to mold larger breasts, firmer buttocks and younger faces.

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Scientists at Oxford and the University of Exeter say that a variant of the FTO gene that is carried by 16 percent of white Europeans made them 70 percent more likely to be obese than those with an alternative variant. Everyone is born is with two copies of the FTO gene, but there are two variants that are inherited. The group at the highest risk was on average 3 kg heavier than the low-risk group, and they carried 15 percent more body weight rather than muscle. The discovery is likely to …

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A team of researchers at University College London say that recent experiments highlight the importance of the gut hormone PYY in obesity. PYY, which is created by high protein diets, send signals to the brain that indicates fullness. Low levels of PYY are associated with cases of obesity. The researchers bred a strain of mice unable to produce PYY to determine the effect of a high-protein diet. The mice ate large amounts of food and became obese. When the mice were treated with PYY, they …

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