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Prostate cancer vaccine proves effective in mice

A prostate cancer vaccine developed at the University of Southern California was able to prevent the disease in 90 percent of mice engineered to develop cancer. And the scientists say that the same Read more...

Hollis-Eden spurs stock price with preclinical news

It's not often that you see a set of preclinical data influence a company's stock price, but Read more...

ALSO NOTED: Wilmut signals new approach to research;Genetic project sheds light on treating hearing loss;

Stem Cell Research

Famed scientist Ian Wilmut says that researchers should remove the nucleus of diseased human cells and inject it into an animal egg which has had the nucleus removed. Once every eight times, that process should deliver a fresh batch of embryonic stem cells that would offer a far more efficient way to test drugs than the current approach involving mice. …

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ALSO NOTED: Research could increase capacity of adult stem cells; potential new class found for prostate cancer;

Stem Cell Research

Working with mouse cells, researchers led by Boris Reizis of Columbia University Medical Center in New York found that the gene Zfx governed self-renewal in embryonic stem cells and in blood-generating hematopoietic adult stem cells. The discovery could have a profound influence on adult stem cell research, which has been restricted by their limited capacity for self-renewal and pluripotency. …

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ALSO NOTED: Hormone promotes prostate cancer; Genetic mutation heightens risk of arrythmia; Search for anti-cancer therapies in

Scientists at the Carbone Comprehensive Cancer Center in Madison, WI have determined that the hormone androgen increases the amount of chemicals in the prostate gland which promotes the development of prostate cancer. And they have found a drug that blocks the pathway, increasing rates of survival and inhibiting tumor development. Report

A team of researchers have …

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ALSO NOTED: Genes identified in ovarian cancer; gene activity predicts metastasis; new transgenic mice developed for leukemia r

More Research

Researchers at McGill University Health Center in Montreal have come up with a new model to identify the specific ovarian cancer genes that are causing the disease. "This model not only allows us to identify the specific human chromosome 3 genes responsible for affecting tumor growth, but also has great potential to pinpoint genes in the entire human genome that would be most affected by this process," said Dr. Patricia Tonin, an …

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Community hospitals find new niche in bioresearch

More community hospitals have decided to launch their own research projects, competing for grant money and publishing their results in peer-reviewed publications. Henry Ford Health System in Detroit, for example, has a $56 million budget to research such topics as the use of gene therapy for prostate cancer. Baylor Health Care System in Houston has increased its research budget to $50 million over just the last six years. For the hospitals, it's a chance to burnish their reputation while …

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ALSO NOTED: Brain cells used to replicate tissue; New research on metastasis; B cells could promote HIV

Scientists at UF McKnight Brain Institute were able to take human brain cells from a mature epilepsy patient to create new brain tissue in mice. "We can theoretically take a single brain cell out of a human being and--with just this one cell--generate enough brain cells to replace every cell of the donor's brain and conceivably those of 50 million other people," said Dennis Steindler, Ph.D., executive director of the institute. "This is a completely new source of human brain cells that …

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Researchers find a possible tumor suppressant

Researchers at the University of Texas M.D. Andersen Cancer Center say they have discovered a single gene--BRT1--that may play a role as a tumor suppressor. BRT1 is under expressed in ovarian, breast and prostate cancer cell lines, say the researchers, whose work is published in Cancer Cell. Defects in the gene inhibit DNA damage response and create genomic instability that fosters the spread of cancer. The researchers conducted lab experiments that showed BRT1 plays a role in …

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