Parkinson Disease news from FierceBioResearcher
News
Skin cells used to treat neurodegenerative disease
Singapore researchers support human/animal chimeras
Gene therapy offers impressive results for Parkinson's
U.K. approves 'cybrids' for stem cell research
Molecule could reverse Parkinson's
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New approaches pursued on Parkinson's
A team of scientists say they have developed a drug that blocks the SIRT2 enzyme, which protects the neurons damaged by Parkinson's disease. In an article to come out this week in the journal Science, researchers at Harvard show how inhibition of SIRT2--a member of the sirtuin family, which is linked to aging--prevents the toxicity of the protein aggregates that are believed to be behind the neuronal death characteristic of PD. Contrary to "classic" approaches that try to …
Read more...Human/animal chimeras get a reprieve in the U.K.
After a huge outcry from scientists and patient groups, the U.K. has proposed legislation allowing the development of human/animal chimera embryos for research. Public Health had proposed banning the chimeras, triggering an outburst from critics who maintain the embryos are crucial for research into Parkinson's and other maladies. The animal/human embryos can be used in place of human eggs, which are often difficult to come by. The substitute is made by removing an animal cell nucleus and …
Read more...Nanomaterials used to fix neuron damage
Northwestern University researcher Samuel Stupp has presented the results of a study in which he injected nanomaterials into the severed spinal cords of mice, allowing them to walk again after several weeks of therapy. The nanomaterials he used were designed to self-assemble into nanofibers which repaired damaged neurons. The research offers new insights into the near-term research potential of nanotechnology and offers hope for patients with Alzheimer's and Parkinson's who suffer from …
Read more...Mayo researchers find trigger for Huntington's
Cynthia T. McMurray, Ph.D., a professor of pharmacology at the Mayo Clinic, led a research team which has shed new light on the way Huntington's disease develops and how it might eventually be treated or cured. The neurodegenerative disease is triggered by an extra segment of the huntingtin gene that expands and produces a destructive protein that afflicts the brain when it grows too large. The researchers determined that the segment grows when cells try to eliminate oxidative lesions. …
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