metabolism news from FierceBioResearcher

The complex genetic machinery that manages our internal body clock is controlled by a single amino acid, which could prove to be one of the biggest new drug targets of the year. Researchers at the Read more...

A new imaging probe has highlighted how the human body's hunger pathways operate, illustrating how new therapies could be developed to tame obesity. Rachel Batterham and a team of researchers at Read more...

There's a race on among scientists to take the lead in creating synthetic life, and a Read more...

Scientists at Penn and Howard Hughes Medical Institute believe that their investigation of the role fat metabolism plays in the development of Type 2 diabetes has pointed to a new drug target. Their focus is a protein that plays a role in fat metabolism. The protein Akt2/PKB prevents fat metabolism by adding a phosphate group to PGC-1a, which is needed to trigger the genes needed for fat metabolism. Both PGC-1a and Akt2/PKB are good targets for new drug development, according to the …

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More Research

An Israeli-U.S. research team has identified a protein that works to combine cells. The work may be particularly significant in repairing damaged cells by getting it to fuse with a therapeutic cell. That could be particularly relevant to diseases of the muscles, bones and other parts which see large numbers of fused cells. Report

Using the worm …

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Scientists at Scripps Research Institute developed a vaccine that allowed rats to eat large quantities of food without getting fat. The vaccine reduces levels of ghrelin, a hormone that regulates the way mammals store fat. Ghrelin was discovered in 1999 and has since been the target of a number of research projects looking for ways to control obesity in humans. In the research project, rats in one group received the vaccine while a control group received inactivated vaccine. Both groups …

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