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RNAi used as nonhormonal contraceptive

A group of researchers at Brigham and Women's Hospital in Boston are focused on developing a new, nonhormonal contraceptive that uses RNAi technology to silence the ZP3 gene, which is required to Read more...

Fat bubbles used to deliver chemo

Tiny fat bubbles can be used to deliver powerful chemotherapy drugs to the site of tumors. Investigators at Duke University have been injecting chemotherapy into fat liposomes and injecting them Read more...

Oklahoma professors unveil new approach to cancer therapy

A pair of scientists at the University of Oklahoma say they have developed a fusion protein that can prevent the spread of cancer. The fusion protein blocks cancer cells from ingesting methionine, a protein they need to develop. The researchers have developed a mechanism that delivers the compound directly to cancer cells, avoiding any damage to healthy cells. The research fits into a broad range of programs looking to develop new ways to deliver cancer therapies without harming healthy …

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Biotech says nano-device can directly target cancer cells

An Australian biotech company says it has developed a "nano-cell" that can be used to directly deliver drugs to cancer cells. Reporting in Cancer Cell journal, EnGeneIC reports the approach worked in primates and promises to help greatly reduce the amount of cancer therapies needed for treatment, while avoiding many of the harsh side effects that are common to chemotherapy. The nano-cell relies on antibodies to dock on the cancer cell for targeted delivery. Researchers hope to begin human …

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Cancer-killing viruses head to the clinic

Oxford University's Leonard Seymour and a group of his colleagues are preparing to move a new approach to fighting cancer into human trials. They've been working on viruses that target cancer cells in the hope that the new approach could be used to replace chemotherapy, which has a host of harsh side effects. In order to make it work, the scientists had to create a polymer coat for the virus to shield it from destruction by the human immune system. That has allowed the virus, in animal …

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Nanoparticles used to destroy tumors

Researchers expect to advance nanoparticle tumor therapies into the clinic this year, hoping to develop a radical new approach to fighting cancer. Researchers at Rice and the University of Texas Health Science Center have been testing nanoparticles in animal models for several years. Tiny, gold-coated spheres are injected into the blood stream and congregate in the tumors. By shining an infrared light through the skin, the researchers can heat up the nanoparticles inside and destroy the …

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