The NIH has recognized 12 leading scientists with its Pioneer Award. They include Emery N. Brown, M.D., Ph.D., who's studying anesthetics; Stanford's Thomas R. Clandinin, Ph.D., who is studying how the brain computes; and James J. Collins, Ph.D., Boston University professor of biomedical engineering, who will develop systems biology and synthetic biology approaches to analyze the bacterial gene regulatory networks underlying cellular responses to antibiotics. Release [1]